PRiME — Next-Generation Precision Medicine

Research

Convergent science, from molecules to medicine

PRiME unites world-class investigators across the University of Toronto, its affiliated hospitals, and global academic and industry partners to address unmet needs in drug discovery, delivery, diagnostics, and disease biology — working at the convergence of science, medicine, and engineering.

Research areas

Six convergent areas of discovery

Biologics & Protein Engineering01

Biologics & Protein Engineering

Recombinant antibody-based therapeutics — the fastest-growing class of drugs — built on Toronto's antibody discovery and commercialization expertise.

Nanomedicine & Biomaterials02

Nanomedicine & Biomaterials

Nanomaterial agents for gene therapy and targeted delivery that concentrate treatment where it's needed and minimize side effects.

Precision Diagnostics03

Precision Diagnostics

Molecular and cellular analysis that tailors treatment to disease subtype and stage — the right therapy for the right patient.

Targeted Small Molecule Therapeutics04

Targeted Small Molecule Therapeutics

Molecular therapeutics for cancer and infectious disease, engineered to balance potency with tolerability.

Biology-on-a-Chip05

Biology-on-a-Chip

Microfluidic devices that model disease biology and enable ex vivo drug testing on a chip.

High-Throughput Omics & Disease Biology06

High-Throughput Omics & Disease Biology

Genomics and proteomics at scale, paired with deep disease-biology expertise across cancer, metabolic disease, and inflammation.

Disease priorities

Three frontiers where precision matters most

Precision Aging

Decoding the biology of aging to keep people healthier for longer.

Precision Oncology

Matching cancer treatment to the molecular signature of each tumour.

Precision Women's Health

Closing long-standing gaps in research and care for women's health.

Bring your research into the PRiME network.

Members access fellowships, global collaborations, and interdisciplinary training across the University of Toronto and its hospitals.